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Category: Drug Development

Drug Development/Philosophy

Do ADHD Drugs Work Longterm?

Posted on February 1, 2012 by James Vornov / 0 Comment

“Illness is the doctor to whom we pay most heed; to kindness, to knowledge, we make promise only; pain we obey.” ― Marcel Proust An essay on ADHD in the New Yor...

Drug Development/Philosophy/Simplifying

Why Enrichment Designs Don’t Work in Clinical Trials

Posted on December 6, 2010 by James Vornov / 1 Comment

Last week I was discussing a clinical trial design with colleagues. This particular trial used an enrichment design. A few years ago I did some simulation work ...

Drug Development

Neurology Notes

Posted on January 9, 2008 by James Vornov / 0 Comment

Not Practicing It looks like I’m not alone in Maryland as a non-practicing physician: State lacks practicing physicians — baltimoresun.com: “W...

Drug Development

Neurology Notes

Posted on January 8, 2008 by James Vornov / 0 Comment

Worth the Subscription I subscribe to the online edition of The Lancet Neurology. The 2007 Round-Up was worth the subscription price itself. I need to keep up v...

Drug Development

Neurology Notes

Posted on January 7, 2008 by James Vornov / 0 Comment

Video: Trepanation Retrospectacle: A Neuroscience Blog: “Trepanation is a procedure where a hole is drilled into the skull, exposing the dura mater and br...

Drug Development

Sol Snyder on Seeking God in the Brain

Posted on January 4, 2008 by James Vornov / 0 Comment

It seems to be Guilford Pharmaceuticals day here. Sol Snyder, scientific founder of Guilford has this wonderful piece in the New England Journal: NEJM — S...

Drug Development

A randomized clinical trial of coenzyme Q10 and GPI-1485 in early Parkinson disease — The NINDS NET-PD Investigators 68 (1): 20 — Neurology

Posted on January 4, 2008 by James Vornov

On the subject of Guilford Pharmaceutical drugs that I’ve worked on, the second NIND NET-PD trial has been published, a futility design that included GPI-...

Drug Development

Aetna to End Payment for a Drug in Colonoscopies – New York Times

Posted on January 4, 2008 by James Vornov / 0 Comment

Of interest: Aetna to End Payment for a Drug in Colonoscopies – New York Times: “Aetna, one of the nation’s largest private health plan manage...

Drug Development

CRO Industry Outlook

Posted on January 3, 2008 by James Vornov

Investor’s Business Daily: Upturn In Biotech Spending Drives Covance’s Growth: “Growth in the CRO sector is driven by biopharmaceutical resear...

Drug Development

Mind Hacks: Personalised drugs

Posted on June 22, 2007 by James Vornov / 0 Comment

Mind Hacks: Personalised drugs: The idea of genetically testing people for drug suitability is causing them [Drug Companies] a bit of a headache at the moment, ...

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