Do ADHD Drugs Work Longterm?
“Illness is the doctor to whom we pay most heed; to kindness, to knowledge, we make promise only; pain we obey.” ― Marcel Proust An essay on ADHD in the New Yor...
Category: Drug Development
Why Enrichment Designs Don’t Work in Clinical Trials
Last week I was discussing a clinical trial design with colleagues. This particular trial used an enrichment design. A few years ago I did some simulation work ...
Neurology Notes
Not Practicing It looks like I’m not alone in Maryland as a non-practicing physician: State lacks practicing physicians — baltimoresun.com: “W...
Neurology Notes
Worth the Subscription I subscribe to the online edition of The Lancet Neurology. The 2007 Round-Up was worth the subscription price itself. I need to keep up v...
Neurology Notes
Video: Trepanation Retrospectacle: A Neuroscience Blog: “Trepanation is a procedure where a hole is drilled into the skull, exposing the dura mater and br...
Sol Snyder on Seeking God in the Brain
It seems to be Guilford Pharmaceuticals day here. Sol Snyder, scientific founder of Guilford has this wonderful piece in the New England Journal: NEJM — S...
A randomized clinical trial of coenzyme Q10 and GPI-1485 in early Parkinson disease — The NINDS NET-PD Investigators 68 (1): 20 — Neurology
On the subject of Guilford Pharmaceutical drugs that I’ve worked on, the second NIND NET-PD trial has been published, a futility design that included GPI-...
Aetna to End Payment for a Drug in Colonoscopies – New York Times
Of interest: Aetna to End Payment for a Drug in Colonoscopies – New York Times: “Aetna, one of the nation’s largest private health plan manage...
CRO Industry Outlook
Investor’s Business Daily: Upturn In Biotech Spending Drives Covance’s Growth: “Growth in the CRO sector is driven by biopharmaceutical resear...
Mind Hacks: Personalised drugs
Mind Hacks: Personalised drugs: The idea of genetically testing people for drug suitability is causing them [Drug Companies] a bit of a headache at the moment, ...